This event is hosted as part of the monthly seminar series featuring leaders in precision medicine from across the nation.
Presented by the Precision Medicine Resource of the Irving Institute for Clinical and Translational Research.
Leveraging Population and Temporal Heterogeneity to Model Risk and Progression in Neurologic Disease
Speaker:
Philip L. De Jager, MD, PhD
Weil-Granat Professor of Neurology
Director, Multiple Sclerosis Center
Director, Center for Translational & Computational Neuroimmunology
Chief, Division of Neuroimmunology
Department of Neurology
Deputy Director, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain
Dr. De Jager will discuss ongoing projects that seek to map the sequence of events that link genetic risk for a disease to a clinical syndrome, with an emphasis on the immune system’s involvement in neurodegenerative diseases including multiple sclerosis and cognitive aging.
For these diseases that develop over years to decades, the propagation of molecular events from genetic risk and environmental risk factors remain poorly understood. We are enumerating these events and how the effect of different variants converge over time. Further, we’ll discuss efforts to map inter-individual sources of variation and the effect of senescence to better resolve disease-related processes.
Date: Thursday, October 20, 2022 from 4:00 - 5:00pm
Location: Hybrid Seminar available via Zoom and In-Person at 622 West 168th St. PH-10-405A/B
